BIOPHARMA LAB PACKAGE
Develop your formulations and therapies faster by combining multiple techniques
Field upgradable to include an autosampler: More data to drive decision making.
When automated, the Nano DSC and Affinity ITC are efficiency-increasing tools that aid in next-level quality design and offer peace of mind throughout development and into clinical phases. The Nano DSC should be a part of every discovery, formulation and R&D testing panel for investigation of novel vaccines, treatments, and testing for COVID-19.
Complete characterization of molecular binding and structure stability
Structure stability, binding affinity, and reaction kinetics are basic chemical characteristics that are required to understand the functional and therapeutic properties of a drug. Reproducible and sensitive tools inform critical decisions.
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
Request More Information
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Modulated DSC®
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
RCS 120 Refrigerated Cooling System
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
High Throughput DSC Autosampler
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
New Microscope Accessory
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
High Throughput DSC Autosampler
It’s hard to believe we could improve on the most reliable DSC autosampler on the market, but we did! The new linear autosampler was designed to be even more rugged and simpler to use than ever before.
The Affinity ITC is a powerful tool for measuring a wide variety of molecular interactions. It provides both inexperienced and advanced ITC users the highest confidence in generating superior ITC data.
Temperature Stability (Standard Volume): 50 µ °C at 25 °C
Features of the Affinity ITC
- AccuShot™ delivers the titrant to the right location for the best mixing
- FlexSpin™ provides innovative slow speed stirring, efficient mixing and highest sensitivity
- Fully automated, user-selectable system cleaning routines eliminate run-to-run contamination
- Intelligent Hardware Positioning for precise reliable injections
- Solid-state active heating and cooling for true isothermal temperature control
- Choice of standard volume (1.0 mL) or low volume cells (190 µL)
- Industry proven 96-well, temperature-controlled liquid handling autosampler.
- Autosampler can be included with initial purchase or added at a later date
- Powerful ITCRun and NanoAnalyze for the most comprehensive suite of tools for method optimization, model fitting, batch analysis, graphing and data export.
The Nano DSC differential scanning calorimeter is designed to characterize the molecular stability of dilute in-solution biomolecules. The Nano DSC obtains data using less sample than competitive designs. Solid-state thermoelectric elements are used to precisely control temperature and a built-in precision linear actuator maintains constant or controlled variable pressure in the cell. Automated, unattended continuous operation with increased sample throughput is achieved with the optional Nano DSC Autosampler.
Temperature Range: -10 °C to 130 °C
Learn More about the Nano DSC
The Nano ITC Standard Volume and Nano ITC Low Volume isothermal titration calorimeters are designed to provide maximum sensitivity and flexibility for the study of biomolecular binding. Both instruments use solid state thermoelectric heating and cooling systems to precisely control temperature, and have the same flexible injection syringe assemblies for efficient and accurate delivery of titrant. The true isothermal power compensation design of the Nano ITC instruments provides the highest sensitivity and flexibility for an ultrasensitive ITC analyzing biological samples in-solution.
Temperature Range (Standard Volume): 2 °C to 80 °C
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
- Fusion Cell™ with patented technology provides unrivaled performance in baseline flatness, sensitivity, resolution, and reproducibility. Its superb technology enables detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity measurements.
- Enhanced Tzero heat flow technology for the X3 guarantees temperature and enthalpy accuracy simultaneously on all three samples
- High-end performance with three sample calorimeters provide unmatched flexibility from replicate testing for statistical analysis to validation/verification against a control sample for the ultimate in certainty
- Modulated DSC® (MDSC®) for the most efficient separation of complex thermal events.
- One-Touch-Away™ User Interface enhances usability and access to data on the instrument.
- Reliable linear autosampler with 54 programmable tray positions for worry-free 24/7 operation, flexible programming of experiments, and automated calibration and verification routines.
- Widest range of refrigerated cooling options eliminates liquid nitrogen expense and ensures uninterrupted sub-ambient operation during extended autosampler routines.
- Tzero Press and pans for fast, simple, and reproducible sample preparation.
- Powerful software that delivers an exceptional user experience in a combined package for instrument control, data analysis, and reporting. Features such as automated calibration routines and real-time test method editing provide unmatched flexibility, while One-Click analysis and custom reporting raise productivity to new levels.
- Commitment to quality backed by the industry’s ONLY five-year cell and furnace warranty for peace of mind.
| Instrument Features | |
|---|---|
| Fusion Cell™ | X3 DSC |
| MDSC |  |
| Enhanced Tzero Heat Flow | |
| User Replaceable Cell | |
| 54-Position Autosampler | |
| Dual Input Gas-Delivery Manifold | |
| Color App-Style Touch Screen | |
| Included |
|
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Modulated DSC®
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
RCS 120 Refrigerated Cooling System
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
High Throughput DSC Autosampler
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
New Microscope Accessory
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
TRIOS Software
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
TRIOS Features & Benefits:
- Control multiple instruments with a single PC and software package
- Overlay and compare results across techniques including DSC, TGA, DMA, SDT and rheometers.
- Unlimited licensing and free lifetime software upgrades.
- One-Click analysis for increased productivity.
- Automated custom report generation including: experimental details, data plots and tables, control charts and analysis results.
- Convenient data export to plain-text, CSV, XML, Excel®, Word®, PowerPoint®, and image formats.
- Optional TRIOS Guardian with electronic signatures for audit trail and data integrity.• Modulated DSC® (MDSC®) for the most efficient separation of complex thermal events.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
TGA Part 2 - Applications
Tuesday, June 23 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
Request More Information
Trade in your Q Series DSC system and SAVE 40% on a NEW Discovery DSC
The world’s finest line of Differential Scanning Calorimeters
Trade in your Q Series DSC system and SAVE 40% on a NEW Discovery DSC
The world’s finest line of Differential Scanning Calorimeters
Technology
Discovery DSC
- New FusionCell™ with patented technology for unrivaled performance
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
How using ITC and DSC techniques together will benefit your lab:
Ease of use and increased efficiency
Samples and Products tested on the Nano DSC and Affinity ITC are label-free, and do not rely on careful immobilization onto the surface of a chip or sensor. Thus, minimal or zero sample preparation is required, which saves time, reduces sample preparation errors, and eliminates optimization of background chemistry (i.e. fluorescence tuning, signal saturation, antibody specificity, etc.).
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
Related Application Notes:
Related Videos:
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery SDT
- Simultaneous DSC/TGA
- Advanced modes for heat capacity, kinetic studies, and better resolution
- Horizontal dual-beam design for superior heat flow and weight measurements
- New 30-position autosampler with programmable tray positions
Discovery TGA
- New ultrasensitive proprietary Tru-Mass™ thermobalance
- The most accurate real-time data
- Superior atmosphere control to meet the most demanding applications
- Rugged & reliable automation
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Learn how the instrument package below will accelerate your biomolecular drug development and offer peace of mind throughout development and into clinical phases.