PHARMACEUTICALS LAB PACKAGE
Develop your formulations and therapies faster by combining techniques
Complete picture of product composition with easily resolved polymorphic peaks in the DSC and microgram-level weight loss detection on the TGA
The DSC 2500 with T4P Heat Flow provides the best true resolution between polymorphic peaks that allows for a clear and accurate measure of the crystalline forms that exist in a sample, and the high-sensitivity balance on the TGA5500 can reproducibility detect even the smallest weight change associated with compounds found in a sample.
Easy storage and stability examination under a wide array of environments with TGA and Modulated DSC
Thermal stability can easily be measured via the TGA without any baseline/blank runs required for baseline subtraction. DSC and MDSC to examine the change in heat capacity allows for clear and easy detection of material compatibility as well as storage stability.
TRIOS Guardian for 21 CFR Part 11 data integrity and data tracking.
TRIOS Guardian plugs into the systems and technologies already in place; TRIOS Guardian is a true file-based system with encapsulated data files, which means audit-controlled data is stored with the file. Free your data and leverage any LIMS, Laboratory notebook, Cloud service, or data processing tools to control when and where you access your data files.
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
Request More Information
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Modulated DSC®
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
RCS 120 Refrigerated Cooling System
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
High Throughput DSC Autosampler
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
New Microscope Accessory
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
High Throughput DSC Autosampler
It’s hard to believe we could improve on the most reliable DSC autosampler on the market, but we did! The new linear autosampler was designed to be even more rugged and simpler to use than ever before.
Differential Scanning Calorimeters (DSC) measure temperatures and heat flows associated with thermal transitions in a material. Common usage includes investigation, selection, comparison and end-use performance evaluation of materials in research, quality control and production applications. Properties measured by TA Instruments’ DSC techniques include glass transitions, “cold” crystallization, phase changes, melting, crystallization, product stability, cure / cure kinetics, and oxidative stability.
Temperature Range: -180°C to 725°C
Detectable Information: Glass transitions, melting, crystallization, phase changes, heat capacity, cure kinetics, oxidative induction time
Thermogravimetric Analyzers measures temperatures and weight changes associated transitions in a material. Common usage includes decomposition, volatilization, residue, material composition analysis, decomposition kinetics, thermal and oxidative stabilities.
Temperature Range: 30°C to 1200°C
Detectable Information: weight change temperature, weight change amount, decomposition kinetics, residue.
21 CFR Part 11 is a section in the Code of Federal Regulations (CFR) that sets forth the United States Food and Drug Administration’s (FDA) guidelines on using electronic records and electronic signatures. Each title of the CFR addresses a different regulated area, 21 CFR relates to Pharmaceuticals and Medical Devices and Part 11 being applicable to electronic records and electronic signatures.
At a high level, Part 11 is a law that ensures that companies and organizations implement good business practices by defining the criteria under which electronic records and signatures are considered to be accurate, authentic, trustworthy, reliable, confidential, and equivalent to paper records and handwritten signatures on paper. Part 11 essentially allows any paper records to be replaced by an electronic record, and allows any handwritten signature to be replaced by an electronic one.
Key Features
- No Database, No licenses and uses existing already defined users.
- Simple, easy to understand
- Allows for normal file handling operations at the IT level.
- LIMS, Cloud and Lab notebook friendly
- No redundancy of storage.
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting for thermal analysis and rheology. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
- Fusion Cell™ with patented technology provides unrivaled performance in baseline flatness, sensitivity, resolution, and reproducibility. Its superb technology enables detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity measurements.
- Enhanced Tzero heat flow technology for the X3 guarantees temperature and enthalpy accuracy simultaneously on all three samples
- High-end performance with three sample calorimeters provide unmatched flexibility from replicate testing for statistical analysis to validation/verification against a control sample for the ultimate in certainty
- Modulated DSC® (MDSC®) for the most efficient separation of complex thermal events.
- One-Touch-Away™ User Interface enhances usability and access to data on the instrument.
- Reliable linear autosampler with 54 programmable tray positions for worry-free 24/7 operation, flexible programming of experiments, and automated calibration and verification routines.
- Widest range of refrigerated cooling options eliminates liquid nitrogen expense and ensures uninterrupted sub-ambient operation during extended autosampler routines.
- Tzero Press and pans for fast, simple, and reproducible sample preparation.
- Powerful software that delivers an exceptional user experience in a combined package for instrument control, data analysis, and reporting. Features such as automated calibration routines and real-time test method editing provide unmatched flexibility, while One-Click analysis and custom reporting raise productivity to new levels.
- Commitment to quality backed by the industry’s ONLY five-year cell and furnace warranty for peace of mind.
| Instrument Features | |
|---|---|
| Fusion Cell™ | X3 DSC |
| MDSC |  |
| Enhanced Tzero Heat Flow | |
| User Replaceable Cell | |
| 54-Position Autosampler | |
| Dual Input Gas-Delivery Manifold | |
| Color App-Style Touch Screen | |
| Included |
|
Revolutionary New Fusion Cell™
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Powerful TRIOS Software
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Modulated DSC®
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
RCS 120 Refrigerated Cooling System
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
High Throughput DSC Autosampler
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
New Microscope Accessory
Revolutionary new Fusion Cell™ further improves the performance on which you’ve come to rely. Better sensitivity, resolution, repeatability and industry leading baseline performance, enable detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity.
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
Refrigerated Cooling Systems (RCS)
Take advantage of the convenient Refrigerated Cooling Systems (RCS) for unattended DSC and MDSC® operation over broad temperature ranges. The new RCS 120 provides enhanced safety and is the only liquid nitrogen-free system capable of conducting experiments down to -120°C.
RCS Features and Benefits:
- One-, Two-, or Three-stage refrigeration systems that achieve temperature ranges down to -40 °C, -90 °C or -120 °C
- Sealed system eliminates the need for liquid nitrogen cooling
- Enables cycling, MDSC®, controlled, and ballistic cooling experiments
- Safe, convenient, and continuous cooling operation for your laboratory needs
TRIOS Software
Discover powerful TRIOS software that delivers exceptional user experience in a combined package for instrument control, data analysis and reporting. New features such as automated calibration routines, multiple calibration sets, real-time test method editing, and inter-laboratory data and test method sharing provide unmatched flexibility, while one-click analysis and custom reporting raise productivity to new levels.
TRIOS Features & Benefits:
- Control multiple instruments with a single PC and software package
- Overlay and compare results across techniques including DSC, TGA, DMA, SDT and rheometers.
- Unlimited licensing and free lifetime software upgrades.
- One-Click analysis for increased productivity.
- Automated custom report generation including: experimental details, data plots and tables, control charts and analysis results.
- Convenient data export to plain-text, CSV, XML, Excel®, Word®, PowerPoint®, and image formats.
- Optional TRIOS Guardian with electronic signatures for audit trail and data integrity.• Modulated DSC® (MDSC®) for the most efficient separation of complex thermal events.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
Ease-of-Use
TRIOS software makes calibration of the entire line of Differential Scanning Calorimeters simple. Users can easily generate multiple calibration data sets under varying experimental conditions (e.g. different heating rates or gas selections) and seamlessly switch between them to match the experimental conditions used for sample testing. Real-time signals and the progress of running experiments is readily available, with the added capability of modifying a running method on the fly. TRIOS software offers a level of flexibility that is unmatched in the industry.
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
TGA Part 2 - Applications
Tuesday, June 23 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
- Theory of operation
- Instrumentation
- Experimental parameters
- Software operation
- Calibration
- Maintenance & Troubleshooting
- Applications
Request More Information
Trade in your Q Series DSC system and SAVE 40% on a NEW Discovery DSC
The world’s finest line of Differential Scanning Calorimeters
Trade in your Q Series DSC system and SAVE 40% on a NEW Discovery DSC
The world’s finest line of Differential Scanning Calorimeters
Technology
Discovery DSC
- New FusionCell™ with patented technology for unrivaled performance
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
How the DSC, TGA, and TRIOS Guardian will benefit your lab:
High sensitivity for detection and accurate quantification of APIs and purity of new formulations during the development and quality control areas of pharmaceuticals
Market leading baseline flatness on both the DSC and TGA create opportunity for easy detection of transitions related to the sample (APIs, excipients, impurities, volatiles) and accurate quantification of those transitions. Understanding the fingerprint of pharmaceutical materials is critical during development/formulation as well as in the area of QC.
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
TGA Part 1 - Theory & Instrumentation
Monday, June 22 at 1:00 pm EDT
This lecture-based course covers all our TGA instruments, but is mainly designed around the Discovery TGA 55, 550, & 5500 instruments. The course will cover:
Related Application Notes:
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery SDT
- Simultaneous DSC/TGA
- Advanced modes for heat capacity, kinetic studies, and better resolution
- Horizontal dual-beam design for superior heat flow and weight measurements
- New 30-position autosampler with programmable tray positions
Discovery TGA
- New ultrasensitive proprietary Tru-Mass™ thermobalance
- The most accurate real-time data
- Superior atmosphere control to meet the most demanding applications
- Rugged & reliable automation
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Discovery DSC
- New FusionCell™ with patented technology for unrivaled baseline flatness, sensitivity, and resolution
- Exclusive Tzero® heat flow technology for ultimate DSC performance
- Unmatched baseline stability that requires no subtractions
- New linear 54-position autosampler
Learn how the instrument package below will accelerate your drug development from formulation to storage optimization, and ensure 21CFR11 compliance.